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Review

May 30, 2024


Leukoaraiosis: Epidemiology, Imaging, Risk Factors, and Management of Age-Related Cerebral White Matter Hyperintensities
Wen-Qing Huang, Qing Lin, Chi-Meng Tzeng
J Stroke. 2024;26(2):131-163.

Leukoaraiosis (LA) manifests as cerebral white matter hyperintensities on T2-weighted magnetic resonance imaging scans and corresponds to white matter lesions or abnormalities in brain tissue. Clinically, it is generally detected...

Review

May 30, 2024


Cancer-Associated Stroke: Thrombosis Mechanism, Diagnosis, Outcome, and Therapeutic Strategies
Ji Hoe Heo, Jaeseob Yun, Kwang Hyun Kim, Jae Wook Jung, Joonsang Yoo, Young Dae Kim, Hyo Suk Nam
J Stroke. 2024;26(2):164-178.

Cancer can induce hypercoagulability, which may lead to stroke. This occurs when tumor cells activate platelets as part of their growth and metastasis. Tumor cells activate platelets by generating thrombin...

Review

May 30, 2024


Prevalence of Cerebral Amyloid Angiopathy Pathology and Strictly Lobar Microbleeds in East-Asian Versus Western Populations: A Systematic Review and Meta-Analysis
Anna M. De Kort, Marcel M. Verbeek, Floris H.B.M. Schreuder, Catharina J.M. Klijn, Lieke Jäkel
J Stroke. 2024;26(2):179-189.

Background and Purpose Possible differences in the prevalence of cerebral amyloid angiopathy (CAA) in East-Asian compared to Western populations have received little attention, and results so far have been ambiguous....

Review

May 30, 2024


Distal Medium Vessel Occlusion Strokes: Understanding the Present and Paving the Way for a Better Future
Raul G. Nogueira, Mohamed F. Doheim, Alhamza R. Al-Bayati, Jin Soo Lee, Diogo C. Haussen, Mahmoud Mohammaden, Michael Lang, Matthew Starr, Marcelo Rocha, Catarina Perry da Câmara, et al.
J Stroke. 2024;26(2):190-202.

Distal medium vessel occlusions (DMVOs) are thought to cause as many as 25% to 40% of all acute ischemic strokes and may result in substantial disability amongst survivors. Although intravenous...

Review

May 30, 2024


Neuroprotective Approaches for Brain Injury After Cardiac Arrest: Current Trends and Prospective Avenues
Subash Marasini, Xiaofeng Jia
J Stroke. 2024;26(2):203-230.

With the implementation of improved bystander cardiopulmonary resuscitation techniques and public-access defibrillation, survival after out-of-hospital cardiac arrest (OHCA) has increased significantly over the years. Nevertheless, OHCA survivors have residual anoxia/reperfusion...

Original Article

May 30, 2024


The Influence of Non-High-Density Lipoprotein Cholesterol on the Efficacy of Genotype-Guided Dual Antiplatelet Therapy in Preventing Stroke Recurrence
Qin Xu, Xia Meng, Hao Li, Xuewei Xie, Jing Jing, Jinxi Lin, Yong Jiang, Yilong Wang, Xingquan Zhao, Zixiao Li, et al.
J Stroke. 2024;26(2):231-241.

Background and Purpose Non-high-density lipoprotein cholesterol (non-HDL-C), which represents the total cholesterol content of all pro-atherogenic lipoproteins, has recently been included as a new target for lipid-lowering therapy in high-risk...

Original Article

May 30, 2024


Device Closure or Antithrombotic Therapy After Cryptogenic Stroke in Elderly Patients With a High-Risk Patent Foramen Ovale
Pil Hyung Lee, Jung-Sun Kim, Jae-Kwan Song, Sun U. Kwon, Bum Joon Kim, Ji Sung Lee, Byung Joo Sun, Jong Shin Woo, Soe Hee Ann, Jung-Won Suh, et al.
J Stroke. 2024;26(2):242-251.

Background and Purpose In young patients (aged 18–60 years) with patent foramen ovale (PFO)-associated stroke, percutaneous closure has been found to be useful for preventing recurrent ischemic stroke or transient...

Original Article

May 30, 2024


How Do Quantitative Tissue Imaging Outcomes in Acute Ischemic Stroke Relate to Clinical Outcomes?
Johanna M. Ospel, Leon Rinkel, Aravind Ganesh, Andrew Demchuk, Manraj Heran, Eric Sauvageau, Manish Joshi, Diogo Haussen, Mahesh Jayaraman, Shelagh Coutts, et al.
J Stroke. 2024;26(2):252-259.

Background and Purpose Infarct volume and other imaging markers are increasingly used as surrogate measures for clinical outcome in acute ischemic stroke research, but how improvements in these imaging surrogates...

Original Article

May 30, 2024


Infarcts Due to Large Vessel Occlusions Continue to Grow Despite Near-Complete Reperfusion After Endovascular Treatment
Johanna M. Ospel, Nathaniel Rex, Karim Oueidat, Rosalie McDonough, Leon Rinkel, Grayson Baird, Scott Collins, Gaurav Jindal, Matthew D. Alvin, Jerrold Boxerman, et al.
J Stroke. 2024;26(2):260-268.

Background and Purpose Infarcts in acute ischemic stroke (AIS) patients may continue to grow even after reperfusion, due to mechanisms such as microvascular obstruction and reperfusion injury. We investigated whether...

Original Article

May 30, 2024


Endovascular Therapy in the Extended Time Window for Large Vessel Occlusion in Patients With Pre-Stroke Disability
Kanta Tanaka, Hiroshi Yamagami, Muhammad M. Qureshi, Kazutaka Uchida, James E. Siegler, Raul G. Nogueira, Shinichi Yoshimura, Nobuyuki Sakai, Nicolas Martinez-Majander, Simon Nagel, et al.
J Stroke. 2024;26(2):269-279.

Background and Purpose We compared the outcomes of endovascular therapy (EVT) in an extended time window in patients with large-vessel occlusion (LVO) between patients with and without pre-stroke disability. Methods In...

Original Article

May 30, 2024


Tenecteplase Versus Alteplase in Medium Vessel Occlusion Ischemic Stroke: A Secondary Analysis of the Alteplase Compared to Tenecteplase Randomized Trial
Fouzi Bala, Nishita Singh, Katrina Ignacio, Ibrahim Alhabli, Ayoola Ademola, Anas Alrohimi, Houman Khosravani, Aleksander Tkach, Luciana Catanese, Dariush Dowlatshahi, et al.
J Stroke. 2024;26(2):280-289.

Background and Purpose The safety and efficacy of tenecteplase in patients with ischemic stroke due to medium vessel occlusion (MeVO) are not well studied. We aimed to compare tenecteplase with...

Original Article

May 30, 2024


Endovascular Thrombectomy Versus Intravenous Thrombolysis of Posterior Cerebral Artery Occlusion Stroke
Silja Räty, Thanh N. Nguyen, Simon Nagel, Davide Strambo, Patrik Michel, Christian Herweh, Muhammad M. Qureshi, Mohamad Abdalkader, Pekka Virtanen, Marta Olive-Gadea, et al.
J Stroke. 2024;26(2):290-299.

Background and Purpose Posterior cerebral artery occlusion (PCAo) can cause long-term disability, yet randomized controlled trials to guide optimal reperfusion strategy are lacking. We compared the outcomes of PCAo patients...

Original Article

May 30, 2024


Deep Learning-Based Automatic Classification of Ischemic Stroke Subtype Using Diffusion-Weighted Images
Wi-Sun Ryu, Dawid Schellingerhout, Hoyoun Lee, Keon-Joo Lee, Chi Kyung Kim, Beom Joon Kim, Jong-Won Chung, Jae-Sung Lim, Joon-Tae Kim, Dae-Hyun Kim, et al.
J Stroke. 2024;26(2):300-311.

Background and Purpose Accurate classification of ischemic stroke subtype is important for effective secondary prevention of stroke. We used diffusion-weighted image (DWI) and atrial fibrillation (AF) data to train a...

Original Article

May 30, 2024


A Multimodal Ensemble Deep Learning Model for Functional Outcome Prognosis of Stroke Patients
Hye-Soo Jung, Eun-Jae Lee, Dae-Il Chang, Han Jin Cho, Jun Lee, Jae-Kwan Cha, Man-Seok Park, Kyung Ho Yu, Jin-Man Jung, Seong Hwan Ahn, et al.
J Stroke. 2024;26(2):312-320.

Background and Purpose The accurate prediction of functional outcomes in patients with acute ischemic stroke (AIS) is crucial for informed clinical decision-making and optimal resource utilization. As such, this study...
Current Issue
Volume 26(2); May 2024
Association of Unfavorable Social Determinants of Health With Stroke/Transient Ischemic Attack and Vascular Risk Factors in Hispanic/Latino Adults: Results From Hispanic Community Health Study/Study of Latinos  (22,236 times)
Gabriela Trifan, Linda C. Gallo, Melissa Lamar, Olga Garcia-Bedoya, Krista M. Perreira, Amber Pirzada, Gregory A. Talavera, Sylvia W. Smoller, Carmen R. Isasi, Jianwen Cai, et al.
J Stroke. 2023;25(3):361-370.

Original Article

August 10, 2023
Neuroimaging of Acute Ischemic Stroke: Multimodal Imaging Approach for Acute Endovascular Therapy  (12,833 times)
Mohamad Abdalkader, James E. Siegler, Jin Soo Lee, Shadi Yaghi, Zhongming Qiu, Xiaochuan Huo, Zhongrong Miao, Bruce C.V. Campbell, Thanh N. Nguyen
J Stroke. 2023;25(1):55-71.

Review

January 31, 2023
Diabetes and Stroke: What Are the Connections?  (12,739 times)
Ofri Mosenzon, Alice YY Cheng, Alejandro A. Rabinstein, Simona Sacco
J Stroke. 2023;25(1):26-38.

Review

January 3, 2023
Endovascular Treatment of Large Vessel Occlusion Strokes Due to Intracranial Atherosclerotic Disease  (12,298 times)
Jin Soo Lee, Seong-Joon Lee, Ji Man Hong, Francisco José Arruda Mont Alverne, Fabricio Oliveira Lima, Raul G. Nogueira
J Stroke. 2022;24(1):3-20.

Review

January 31, 2022
Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality  (11,220 times)
Thanh N. Nguyen, Muhammad M. Qureshi, Piers Klein, Hiroshi Yamagami, Mohamad Abdalkader, Robert Mikulik, Anvitha Sathya, Ossama Yassin Mansour, Anna Czlonkowska, Hannah Lo, et al.
J Stroke. 2022;24(2):256-265.Correction in: J Stroke 2024;26(1):129

Original Article

May 31, 2022
Collateral Circulation in Ischemic Stroke: An Updated Review  (10,048 times)
Gino Maguida, Ashfaq Shuaib
J Stroke. 2023;25(2):179-198.

Review

March 13, 2023
2022 Update of the Korean Clinical Practice Guidelines for Stroke: Antithrombotic Therapy for Patients with Acute Ischemic Stroke or Transient Ischemic Attack  (9,942 times)
Hong-Kyun Park, Sang-Bae Ko, Keun-Hwa Jung, Min Uk Jang, Dae-Hyun Kim, Joon-Tae Kim, Jay Chol Choi, Hye Seon Jeong, Chulho Kim, Ji Hoe Heo, et al.
J Stroke. 2022;24(1):166-175.

Guideline

January 31, 2022
Stroke in Women: A Review Focused on Epidemiology, Risk Factors, and Outcomes  (9,172 times)
Cindy W. Yoon, Cheryl D. Bushnell
J Stroke. 2023;25(1):2-15.

Review

January 31, 2023
Endovascular Treatment for Posterior Circulation Stroke: Ways to Maximize Therapeutic Efficacy  (8,878 times)
Seong-Joon Lee, Ji Man Hong, Jong S. Kim, Jin Soo Lee
J Stroke. 2022;24(2):207-223.

Review

May 31, 2022
Hypertriglyceridemia: A Neglected Risk Factor for Ischemic Stroke?  (8,253 times)
Hai-jie Liang, Qing-yi Zhang, Yi-tong Hu, Guo-qing Liu, Rong Qi
J Stroke. 2022;24(1):21-40.

Review

January 31, 2022
Mechanical Thrombectomy Access for All? Challenges in Increasing Endovascular Treatment for Acute Ischemic Stroke in the United States  (7,548 times)
Sushanth Rao Aroor, Kaiz S. Asif, Jennifer Potter-Vig, Arun Sharma, Bijoy K. Menon, Violiza Inoa, Cynthia B. Zevallos, Jose G. Romano, Santiago Ortega-Gutierrez, Larry B. Goldstein, et al.
J Stroke. 2022;24(1):41-48.

Review

January 31, 2022
Anger, a Result and Cause of Stroke: A Narrative Review  (7,247 times)
Smi Choi-Kwon, Jong S. Kim
J Stroke. 2022;24(3):311-322.

Review

September 30, 2022
Bridging Thrombolysis versus Direct Mechanical Thrombectomy in Stroke Due to Basilar Artery Occlusion  (7,189 times)
Isabel Siow, Benjamin Y.Q. Tan, Keng Siang Lee, Natalie Ong, Emma Toh, Anil Gopinathan, Cunli Yang, Pervinder Bhogal, Erika Lam, Oliver Spooner, et al.
J Stroke. 2022;24(1):128-137.

Original Article

January 31, 2022
Association of Lipids, Lipoproteins, and Apolipoproteins with Stroke Subtypes in an International Case Control Study (INTERSTROKE)  (7,161 times)
Martin J. O’Donnell, Matthew McQueen, Allan Sniderman, Guillaume Pare, Xingyu Wang, Graeme J. Hankey, Sumathy Rangarajan, Siu Lim Chin, Purnima Rao-Melacini, John Ferguson, et al.
J Stroke. 2022;24(2):224-235.

Original Article

May 31, 2022
Predictors of Therapy Response in Chronic Aphasia: Building a Foundation for Personalized Aphasia Therapy  (7,122 times)
Sigfus Kristinsson, Dirk B. den Ouden, Chris Rorden, Roger Newman-Norlund, Jean Neils-Strunjas, Julius Fridriksson
J Stroke. 2022;24(2):189-206.

Review

May 31, 2022
Establishment of the Heart and Brain Team for Patent Foramen Ovale Closure in Stroke Patients: An Expert Opinion  (7,116 times)
Jong S. Kim, Vincent Thijs, Matias Yudi, Kazunori Toyoda, Masayuki Shiozawa, Jin Zening, Brian Clapp, Bert Albers, Hans-Christoph Diener
J Stroke. 2022;24(3):345-351.

Review

September 30, 2022
Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study  (6,942 times)
Qi Wang, Huajie Dai, Tianzhichao Hou, Yanan Hou, Tiange Wang, Hong Lin, Zhiyun Zhao, Mian Li, Ruizhi Zheng, Shuangyuan Wang, et al.
J Stroke. 2023;25(3):350-360.

Original Article

September 26, 2023
Endovascular versus Medical Management of Acute Basilar Artery Occlusion: A Systematic Review and Meta-Analysis of the Randomized Controlled Trials  (6,901 times)
Mohamad Abdalkader, Stephanos Finitsis, Chuanhui Li, Wei Hu, Xinfeng Liu, Xunming Ji, Xiaochuan Huo, Fana Alemseged, Zhongming Qiu, Daniel Strbian, et al.
J Stroke. 2023;25(1):81-91.

Review

January 31, 2023
Smartphone App in Stroke Management: A Narrative Updated Review  (6,881 times)
Adriano Bonura, Francesco Motolese, Fioravante Capone, Gianmarco Iaccarino, Michele Alessiani, Mario Ferrante, Rosalinda Calandrelli, Vincenzo Di Lazzaro, Fabio Pilato
J Stroke. 2022;24(3):323-334.Correction in: J Stroke 2023;25(2):320

Review

September 30, 2022
Sex and Gender Differences in Stroke and Their Practical Implications in Acute Care  (6,849 times)
Johanna Ospel, Nishita Singh, Aravind Ganesh, Mayank Goyal
J Stroke. 2023;25(1):16-25.

Review

January 31, 2023
Etiology, 3-Month Functional Outcome and Recurrent Events in Non-Traumatic Intracerebral Hemorrhage  (6,723 times)
Martina B. Goeldlin, Achim Mueller, Bernhard M. Siepen, Madlaine Mueller, Davide Strambo, Patrik Michel, Michael Schaerer, Carlo W. Cereda, Giovanni Bianco, Florian Lindheimer, et al.
J Stroke. 2022;24(2):266-277.

Original Article

May 31, 2022
Long-Term Follow-up of Enhanced Holter-Electrocardiography Monitoring in Acute Ischemic Stroke  (6,668 times)
Rolf Wachter, Mark Weber-Krüger, Gerhard F. Hamann, Pawel Kermer, Jan Liman, Meinhard Mende, Joachim Seegers, Katrin Wasser, Sonja Gröschel, Timo Uphaus, et al.
J Stroke. 2022;24(1):98-107.

Original Article

December 17, 2021
Trends in Stroke Presentations before and during the COVID-19 Pandemic: A Meta-Analysis  (6,457 times)
Noman Ishaque, Asif Javed Butt, Joseph Kamtchum-Tatuene, Ali Zohair Nomani, Sarah Razzaq, Nida Fatima, Chetan Vekhande, Radhika Nair, Naveed Akhtar, Khurshid Khan, et al.
J Stroke. 2022;24(1):65-78.

Original Article

January 31, 2022
Replacing Alteplase with Tenecteplase: Is the Time Ripe?  (6,380 times)
Nishita Singh, Bijoy K. Menon, Adam A. Dmytriw, Robert W. Regenhardt, Joshua A. Hirsch, Aravind Ganesh
J Stroke. 2023;25(1):72-80.

Review

January 31, 2023
The Challenge of Designing Stroke Trials That Change Practice: MCID vs. Sample Size and Pragmatism  (6,170 times)
Mayank Goyal, Rosalie McDonough, Marc Fisher, Johanna Ospel
J Stroke. 2022;24(1):49-56.

Special Review

January 31, 2022
Update of Anticoagulation Use in Cardioembolic Stroke With a Special Reference to Endovascular Treatment  (6,140 times)
Apostolos Safouris, Klearchos Psychogios, Lina Palaiodimou, Peter Orosz, George Magoufis, Odysseas Kargiotis, Aikaterini Theodorou, Theodore Karapanayiotides, Stavros Spiliopoulos, Sándor Nardai, et al.
J Stroke. 2024;26(1):13-25.

Review

January 30, 2024
DIRECT-SAFE: A Randomized Controlled Trial of DIRECT Endovascular Clot Retrieval versus Standard Bridging Therapy  (6,126 times)
Peter J. Mitchell, Bernard Yan, Leonid Churilov, Richard J. Dowling, Steven Bush, Thang Nguyen, Bruce C.V. Campbell, Geoffrey A. Donnan, Zhongrong Miao, Stephen M. Davis, et al.
J Stroke. 2022;24(1):57-64.

Protocol

January 31, 2022
Causal Relations between Exposome and Stroke: A Mendelian Randomization Study  (6,075 times)
Hong-Qi Li, Yi-Wei Feng, Yu-Xiang Yang, Xin-Yi Leng, Prof Can Zhang, Shi-Dong Chen, Kevin Kuo, Shu-Yi Huang, Xue-Qing Zhang, Yi Dong, et al.
J Stroke. 2022;24(2):236-244.

Original Article

May 31, 2022
Venous Outflow Profiles Are Linked to Clinical Outcomes in Ischemic Stroke Patients with Extensive Baseline Infarct  (5,899 times)
Laurens Winkelmeier, Gabriel Broocks, Helge Kniep, Vincent Geest, Jonathan Reinwald, Lukas Meyer, Noel van Horn, Adrien Guenego, Kamil Zeleňák, Gregory W. Albers, et al.
J Stroke. 2022;24(3):372-382.

Original Article

September 30, 2022
Moderate-Intensity Rosuvastatin Plus Ezetimibe Versus High-Intensity Rosuvastatin for Target Low-Density Lipoprotein Cholesterol Goal Achievement in Patients With Recent Ischemic Stroke: A Randomized Controlled Trial  (5,825 times)
Keun-Sik Hong, Oh Young Bang, Jong-Ho Park, Jin-Man Jung, Sang-Hun Lee, Tae-Jin Song, Hyo Suk Nam, Hee-Kwon Park, Keun-Hwa Jung, Sung Hyuk Heo, et al.
J Stroke. 2023;25(2):242-250.

Original Article

April 11, 2023
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