Treatments to Promote Neural Repair after Stroke
Steven C. Cramer
J Stroke. 2018;20(1):57-70.   Published online 2018 Jan 31     DOI: https://doi.org/10.5853/jos.2017.02796
Citations to this article as recorded by Crossref logo
Bone marrow mesenchymal stem cells therapy regulates sphingolipid and glycerophospholipid metabolism to promote neurological recovery in stroke rats: A metabolomics analysis
Shixin Xu, Aiqin Zhong, Yunsha Zhang, Linna Zhao, Yuying Guo, Xiaodan Bai, Penglin Yin, Shengyu Hua
Experimental Neurology.2024; 372: 114619.     CrossRef
Endogenous defense mechanism-based neuroprotection in large-vessel acute ischemic stroke: A hope for future
Deepak Goel, Sushant Shangari, Manish Mittal, Ashwani Bhat
Brain Circulation.2024; 10(1): 51.     CrossRef
Cerebral stroke-induced neurogenesis: insights and therapeutic implications
Mydhili Radhakrishnan, Roli Kushwaha, B. Supraja Acharya, Arvind Kumar, Sumana Chakravarty
Exploration of Neuroprotective Therapy.2024; : 172.     CrossRef
Amphetamine and methylphenidate potential on the recovery from stroke and traumatic brain injury: a review
Mariana Ferreira, Patrícia Carneiro, Vera Marisa Costa, Félix Carvalho, Andreas Meisel, João Paulo Capela
Reviews in the Neurosciences.2024;[Epub]     CrossRef
Translational Medicine in Acute Ischemic Stroke and Traumatic Brain Injury—NeuroAiD Trials, from Traditional Beliefs to Evidence-Based Therapy
Narayanaswamy Venketasubramanian, Tseng Tsai Yeo, Christopher Li Hsian Chen
Biomolecules.2024; 14(6): 680.     CrossRef
Therapeutic effectiveness of Donepezil hydrochloride in combination with butylphthalide for post-stroke cognitive impairment
Yuxin Pang
American Journal of Translational Research.2024; 16(6): 2719.     CrossRef
Clozapine-Induced Chemogenetic Neuromodulation Rescues Post-Stroke Deficits After Chronic Capsular Infarct
Jongwook Cho, Seungjun Ryu, Sunwoo Lee, Junsoo Kim, Ji-Young Park, Hyuk-Sang Kwon, Hyoung-Ihl Kim
Translational Stroke Research.2023; 14(4): 499.     CrossRef
Maf1 is an intrinsic suppressor against spontaneous neural repair and functional recovery after ischemic stroke
Chi Kwan Tsang, Qiongjie Mi, Guangpu Su, Gum Hwa Lee, Xuemin Xie, Gabriella D'Arcangelo, Li'an Huang, X.F. Steven Zheng
Journal of Advanced Research.2023; 51: 73.     CrossRef
High‐frequency repetitive magnetic stimulation rescues ischemia‐injured neurons through modulation of glial‐derived neurotrophic factor present in the astrocyteʼs secretome
Genilso Gava‐Junior, Susana A. Ferreira, Cláudio Roque, Julieta Mendes‐Oliveira, Inês Serrenho, Nuno Pinto, Maria Vaz Patto, Graça Baltazar
Journal of Neurochemistry.2023; 164(6): 813.     CrossRef
Clinical experience: Outcomes of mesenchymal stem cell transplantation in five stroke patients
Nesrin Ercelen, Nilgun Karasu, Bulent Kahyaoglu, Onder Cerezci, Rana Cagla Akduman, Defne Ercelen, Gizem Erturk, Gokay Gulay, Nagihan Alpaydin, Gizem Boyraz, Berrin Monteleone, Zekiye Kural, Hakan Silek, Sibel Temur, Canan Aykut Bingol
Frontiers in Medicine.2023;[Epub]     CrossRef
A Meta-Analysis on Dual Protocols for Chronic Stroke Motor Recovery: Robotic Training and tDCS
Rye-Kyeong Kim, Nyeonju Kang, Zeel Desai, James H. Cauraugh
Applied Sciences.2023; 13(3): 1992.     CrossRef
Pathogenomic Signature and Aberrant Neurogenic Events in Experimental Cerebral Ischemic Stroke: A Neurotranscriptomic-Based Implication for Dementia
Syed Aasish Roshan, Gayathri Elangovan, Dharani Gunaseelan, Swaminathan K. Jayachandran, Mahesh Kandasamy, Muthuswamy Anusuyadevi, KS Jagannatha Rao, Lezanne Ooi, Muralidhar L. Hegde, Yan Zhang, Nancy Y. Ip, Mohammad Nami, Mikko Hiltunen, John Jia En Chua
Journal of Alzheimer's Disease.2023; 94(s1): S289.     CrossRef
Circular RNA CircPDS5B impairs angiogenesis following ischemic stroke through its interaction with hnRNPL to inactivate VEGF-A
Zhongzhong Jiang, Yugang Jiang
Neurobiology of Disease.2023; 181: 106080.     CrossRef
The Future Trajectory of Stroke Management: A Birds Eye View of Hope
Prithvijit Chakraborty
Neurology India.2023; 71(2): 357.     CrossRef
Therapies and Challenges in the Post-Stroke Aphasia Rehabilitation Arena: Current and Future Prospects
Anastasios M. Georgiou, Maria Kambanaros
Medicina.2023; 59(9): 1674.     CrossRef
Regulation of Dihydropyrimidinase-like 3 Gene Expression by MicroRNAs in PC12 Cells with Induced Ischaemia and Hypothermia
Kisang Kwon, Ji-Hye Song, Hyewon Park, O-Yu Kwon, Seung-Whan Kim
Folia Biologica.2023; 69(2): 69.     CrossRef
Contralateral S1 function is involved in electroacupuncture treatment-mediated recovery after focal unilateral M1 infarction
Lu-Lu Yao, Si Yuan, Zhen-Nan Wu, Jian-Yu Luo, Xiao-Rong Tang, Chun-Zhi Tang, Shuai Cui, Neng-Gui Xu
Neural Regeneration Research.2022; 17(6): 1310.     CrossRef
Cellular and Molecular Targets for Non-Invasive, Non-Pharmacological Therapeutic/Rehabilitative Interventions in Acute Ischemic Stroke
Gelu Onose, Aurelian Anghelescu, Dan Blendea, Vlad Ciobanu, Cristina Daia, Florentina Firan, Mihaela Oprea, Aura Spinu, Cristina Popescu, Anca Ionescu, Ștefan Busnatu, Constantin Munteanu
International Journal of Molecular Sciences.2022; 23(2): 907.     CrossRef
The Genetic Basis of Strokes in Pediatric Populations and Insight into New Therapeutic Options
Milena Jankovic, Bojana Petrovic, Ivana Novakovic, Slavko Brankovic, Natasa Radosavljevic, Dejan Nikolic
International Journal of Molecular Sciences.2022; 23(3): 1601.     CrossRef
Non-invasive brain stimulation as therapeutic approach for ischemic stroke: Insights into the (sub)cellular mechanisms
Hannelore Kemps, Pascal Gervois, Bert Brône, Robin Lemmens, Annelies Bronckaers
Pharmacology & Therapeutics.2022; 235: 108160.     CrossRef
Neurodegenerative effect of DAPK1 after cerebral hypoxia-ischemia is associated with its post-transcriptional and signal transduction regulations: A systematic review and meta-analysis
Zeeshan Ahmad Khan, Dewan Md. Sumsuzzman, Jeonghyun Choi, Yonggeun Hong
Ageing Research Reviews.2022; 76: 101593.     CrossRef
Effects of combining two techniques of non-invasive brain stimulation in subacute stroke patients: a pilot study
Sutthikit Pipatsrisawat, Jakkrit Klaphajone, Kittipong Kitisak, Somporn Sungkarat, Pakorn Wivatvongvana
BMC Neurology.2022;[Epub]     CrossRef
Functional profiles derived from the ICF Generic set and the responsiveness and validity of the Generic-6 set's Functioning score among persons after stroke
Johanna JONSDOTTIR, Thomas BOWMAN, Anna CASIRAGHI, Marina RAMELLA, Angelo MONTESANO
European Journal of Physical and Rehabilitation Medicine.2022;[Epub]     CrossRef
Brain delivering RNA-based therapeutic strategies by targeting mTOR pathway for axon regeneration after central nervous system injury
Ming-Xi Li, Jing-Wen Weng, EricS Ho, ShingFung Chow, ChiKwan Tsang
Neural Regeneration Research.2022; 17(10): 2157.     CrossRef
Post-stroke enriched auditory environment induces structural connectome plasticity: secondary analysis from a randomized controlled trial
Aleksi J. Sihvonen, Seppo Soinila, Teppo Särkämö
Brain Imaging and Behavior.2022; 16(4): 1813.     CrossRef
Pre‐ and post‐conditioning with poly I:C exerts neuroprotective effect against cerebral ischemia injury in animal models: A systematic review and meta‐analysis
Zeeshan Ahmad Khan, Dewan Md. Sumsuzzman, Jeonghyun Choi, George Kamenos, Yonggeun Hong
CNS Neuroscience & Therapeutics.2022; 28(8): 1168.     CrossRef
COMPREHENSIVE STUDY OF MANIFESTATIONS OF BRAIN TISSUE RESOLUTION IN CASE OF VARIOUS TYPES OF STROKE
Ruslana I. Falion, Yuliya I. Beketova, Yuriy O. Pospishil
Wiadomości Lekarskie.2022; 75(4): 791.     CrossRef
Sirtuins and cognition: implications for learning and memory in neurological disorders
Eric Fagerli, Iris Escobar, Fernando J. Ferrier, Charles W. Jackson, Efrain J. Perez-Lao, Miguel A. Perez-Pinzon
Frontiers in Physiology.2022;[Epub]     CrossRef
A Novel In Vivo Model for Multiplexed Analysis of Callosal Connections upon Cortical Damage
Ana González-Manteiga, Carmen Navarro-González, Valentina Evita Sebestyén, Jose Manuel Saborit-Torres, Daniela Talhada, María de la Iglesia Vayá, Karsten Ruscher, Pietro Fazzari
International Journal of Molecular Sciences.2022; 23(15): 8224.     CrossRef
New Strategies for Stroke Therapy: Nanoencapsulated Neuroglobin
Santos Blanco, Esther Martínez-Lara, Eva Siles, María Ángeles Peinado
Pharmaceutics.2022; 14(8): 1737.     CrossRef
Crosstalk among N6-methyladenosine modification and RNAs in central nervous system injuries
Mi Tian, Lei Mao, Li Zhang
Frontiers in Cellular Neuroscience.2022;[Epub]     CrossRef
Impact of Telerehabilitation for Stroke-Related Deficits
Kurt D. Knepley, Jennifer Z. Mao, Peter Wieczorek, Frederick O. Okoye, Abhi P. Jain, Noam Y. Harel
Telemedicine and e-Health.2021; 27(3): 239.     CrossRef
Ten key reasons for continuing research on pharmacotherapy for post-stroke aphasia
Marcelo L. Berthier
Aphasiology.2021; 35(6): 824.     CrossRef
Impact of SMTP Targeting Plasminogen and Soluble Epoxide Hydrolase on Thrombolysis, Inflammation, and Ischemic Stroke
Keiji Hasumi, Eriko Suzuki
International Journal of Molecular Sciences.2021; 22(2): 954.     CrossRef
Delayed Treatment with Human Dental Pulp Stem Cells Accelerates Functional Recovery and Modifies Responses of Peri-Infarct Astrocytes Following Photothrombotic Stroke in Rats
Wai Ping Yew, Natalia D. Djukic, Jaya S. P. Jayaseelan, Xenia Kaidonis, Karlea L. Kremer, Fong Chan Choy, Richard J. Woodman, Simon A. Koblar, Neil R. Sims
Cell Transplantation.2021; 30: 096368972098443.     CrossRef
Rehabilitation and Biomarkers of Stroke Recovery: Study Protocol for a Randomized Controlled Trial
Alessandro Picelli, Mirko Filippetti, Lidia Del Piccolo, Federico Schena, Leonardo Chelazzi, Chiara Della Libera, Massimo Donadelli, Valeria Donisi, Paolo Francesco Fabene, Stefania Fochi, Cristina Fonte, Marialuisa Gandolfi, Macarena Gomez-Lira, Elena Lo
Frontiers in Neurology.2021;[Epub]     CrossRef
Effect of Tetramethylpyrazine on Neuroplasticity after Transient Focal Cerebral Ischemia Reperfusion in Rats
Junbin Lin, Chizi Hao, Yu Gong, Ying Zhang, Ying Li, Zhihe Feng, Xiangdong Xu, Hailong Huang, Weijing Liao, Pawe Zalewski
Evidence-Based Complementary and Alternative Medicine.2021; 2021: 1.     CrossRef
Effects of mechanical thrombectomy for post-stroke patients with upper limb hemiparesis: Use of Propensity Score Matching
Kazuhiro Tokuda, Takashi Takebayashi, Takashi Koyama, Toshiaki Fujita, Keisuke Hanada, Yuho Okita
Clinical Neurology and Neurosurgery.2021; 202: 106520.     CrossRef
Does rTMS Targeting Contralesional S1 Enhance Upper Limb Somatosensory Function in Chronic Stroke? A Proof-of-Principle Study
Svetlana Pundik, Margaret Skelly, Jessica McCabe, Heba Akbari, Curtis Tatsuoka, Ela B. Plow
Neurorehabilitation and Neural Repair.2021; 35(3): 233.     CrossRef
Astrocytes contribute to the neuronal recovery promoted by high‐frequency repetitive magnetic stimulation in in vitro models of ischemia
Cláudio Roque, Nuno Pinto, Maria Vaz Patto, Graça Baltazar
Journal of Neuroscience Research.2021; 99(5): 1414.     CrossRef
SCO-spondin-derived Peptide Protects Neurons from Glutamate-induced Excitotoxicity
Nathalie Delétage, Juliette Le Douce, Noëlle Callizot, Yann Godfrin, Sighild Lemarchant
Neuroscience.2021; 463: 317.     CrossRef
A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects
T. Lencioni, L. Fornia, T. Bowman, A. Marzegan, A. Caronni, A. Turolla, J. Jonsdottir, I. Carpinella, M. Ferrarin
Scientific Reports.2021;[Epub]     CrossRef
Pien-Tze-Huang, a Chinese patent formula, attenuates NLRP3 inflammasome-related neuroinflammation by enhancing autophagy via the AMPK/mTOR/ULK1 signaling pathway
Zhenwei Huang, Xian Zhou, Xiaoqin Zhang, Lili Huang, Yibin Sun, Zaixing Cheng, Wen Xu, Chun-Guang Li, Yanfang Zheng, Mingqing Huang
Biomedicine & Pharmacotherapy.2021; 141: 111814.     CrossRef
Differential effects of the cell cycle inhibitor, olomoucine, on functional recovery and on responses of peri-infarct microglia and astrocytes following photothrombotic stroke in rats
Wai Ping Yew, Natalia D. Djukic, Jaya S. P. Jayaseelan, Richard J. Woodman, Hakan Muyderman, Neil R. Sims
Journal of Neuroinflammation.2021;[Epub]     CrossRef
Novel Advances to Post-Stroke Aphasia Pharmacology and Rehabilitation
Natalia Cichon, Lidia Wlodarczyk, Joanna Saluk-Bijak, Michal Bijak, Justyna Redlicka, Leslaw Gorniak, Elzbieta Miller
Journal of Clinical Medicine.2021; 10(17): 3778.     CrossRef
Hyaluronic Acid and Regenerative Medicine: New Insights into the Stroke Therapy
Maryam Shahi, Daruosh Mohammadnejad, Mohammad Karimipour, Seyed Hossein Rasta, Reza Rahbarghazi, Ali Abedelahi
Current Molecular Medicine.2021; 20(9): 675.     CrossRef
Biological Implications of a Stroke Therapy Based in Neuroglobin Hyaluronate Nanoparticles. Neuroprotective Role and Molecular Bases
María Ángeles Peinado, David Ovelleiro, María Luisa del Moral, Raquel Hernández, Esther Martínez-Lara, Eva Siles, José Rafael Pedrajas, María Luisa García-Martín, Carlos Caro, Sebastián Peralta, María Encarnación Morales, María Adolfina Ruiz, Santos Blanc
International Journal of Molecular Sciences.2021; 23(1): 247.     CrossRef
Vocal Music Listening Enhances Poststroke Language Network Reorganization
Aleksi J. Sihvonen, Pablo Ripollés, Vera Leo, Jani Saunavaara, Riitta Parkkola, Antoni Rodríguez-Fornells, Seppo Soinila, Teppo Särkämö
eneuro.2021; 8(4): ENEURO.0158-21.2021.     CrossRef
Non-Invasive Brain Stimulation as Therapeutic Approach for Ischemic Stroke: Insights into the (Sub)Cellular Mechanisms
Hannelore Kemps, Pascal gervois, Bert Brône, Robin Lemmens, Annelies Bronckaers
SSRN Electronic Journal .2021;[Epub]     CrossRef
Bimanual Coordination Functions between Paretic and Nonparetic Arms: A Systematic Review and Meta-analysis
Rye Kyeong Kim, Nyeonju Kang
Journal of Stroke and Cerebrovascular Diseases.2020; 29(2): 104544.     CrossRef
Translating concepts of neural repair after stroke: Structural and functional targets for recovery
Robert W. Regenhardt, Hajime Takase, Eng H. Lo, David J. Lin
Restorative Neurology and Neuroscience.2020; 38(1): 67.     CrossRef
Effects of robot therapy on upper body kinematics and arm function in persons post stroke: a pilot randomized controlled trial
Ilaria Carpinella, Tiziana Lencioni, Thomas Bowman, Rita Bertoni, Andrea Turolla, Maurizio Ferrarin, Johanna Jonsdottir
Journal of NeuroEngineering and Rehabilitation.2020;[Epub]     CrossRef
Effect of acetylcholinesterase inhibitors on post-stroke cognitive impairment and vascular dementia: A meta-analysis
Jin Ok Kim, Soo Joo Lee, Jung-Soo Pyo, Stephen D Ginsberg
PLOS ONE.2020; 15(2): e0227820.     CrossRef
A Novel Intervention Platform for Service Members With Subjective Cognitive Complaints: Implementation, Patient Participation, and Satisfaction
Katherine W Sullivan, Wendy A Law, Laura Loyola, Martin A Knoll, Daniel E Shub, Louis M French
Military Medicine.2020; 185(Supplement): 326.     CrossRef
Recovery After Stroke
Steven C. Cramer
CONTINUUM: Lifelong Learning in Neurology.2020; 26(2): 415.     CrossRef
Predictors of Neurological and Functional Recovery in Patients with Moderate to Severe Ischemic Stroke: The EPICA Study
Manuel Murie-Fernández, Mercedes Molleda Marzo
Stroke Research and Treatment.2020; 2020: 1.     CrossRef
Intranasal Dexamethasone Reduces Mortality and Brain Damage in a Mouse Experimental Ischemic Stroke Model
Alejandro Espinosa, Gabriela Meneses, Anahí Chavarría, Raúl Mancilla, José Pedraza-Chaverri, Agnes Fleury, Brandon Bárcena, Ivan N. Pérez-Osorio, Hugo Besedovsky, Antonio Arauz, Gladis Fragoso, Edda Sciutto
Neurotherapeutics.2020; 17(4): 1907.     CrossRef
RETRACTED: Escitalopram improves neural functional prognosis and endothelial dysfunction in patients with acute cerebral infarction
Jin-Xia Cao, Li Liu, Yun-Tao Sun, Qing-Hong Zeng, Zhen-Dong Yang, Jie-Chun Chen
Restorative Neurology and Neuroscience.2020; 38(5): 385.     CrossRef
Continuous administration of a p38α inhibitor during the subacute phase after transient ischemia-induced stroke in the rat promotes dose-dependent functional recovery accompanied by increase in brain BDNF protein level
John J. Alam, Michael Krakovsky, Ursula Germann, Aharon Levy, Marietta Zille
PLOS ONE.2020; 15(12): e0233073.     CrossRef
TGFβ1 Induces Axonal Outgrowth via ALK5/PKA/SMURF1-Mediated Degradation of RhoA and Stabilization of PAR6
Julia Kaiser, Martina Maibach, Ester Piovesana, Iris Salpeter, Nora Escher, Yannick Ormen, Martin E. Schwab
eneuro.2020; 7(5): ENEURO.0104-20.2020.     CrossRef
miR-9 Upregulation Integrates Post-ischemic Neuronal Survival and Regeneration In Vitro
Sreekala S. Nampoothiri, G. K. Rajanikant
Cellular and Molecular Neurobiology.2019; 39(2): 223.     CrossRef
Nucleic Acid Therapies for Ischemic Stroke
Nils Henninger, Yunis Mayasi
Neurotherapeutics.2019; 16(2): 299.     CrossRef
Angioneurins – Key regulators of blood–brain barrier integrity during hypoxic and ischemic brain injury
Reiner Kunze, Hugo H. Marti
Progress in Neurobiology.2019; 178: 101611.     CrossRef
Activation of GABAA receptors enhances the behavioral recovery but not axonal sprouting in ischemic rats
Huibin Wang, Xi Cheng, Hang Yu, Xiuchun Zhang, Meiting Guan, Lanqing Zhao, Yang Liu, Yifan Linag, Yujia Luo, Chuansheng Zhao
Restorative Neurology and Neuroscience.2019; 37(4): 315.     CrossRef
On the Recovery after Stroke: When and What Should We Focus on?
Jae-Sung Lim
Journal of Korean Medical Science.2019;[Epub]     CrossRef
Digital Therapeutics: Emerging New Therapy for Neurologic Deficits after Stroke
Mi Joo Choi, Hana Kim, Hyun-Wook Nah, Dong-Wha Kang
Journal of Stroke.2019; 21(3): 242.     CrossRef
Robot-Assisted Stair Climbing Training on Postural Control and Sensory Integration Processes in Chronic Post-stroke Patients: A Randomized Controlled Clinical Trial
Marialuisa Gandolfi, Nicola Valè, Eleonora Dimitrova, Maria Elisabetta Zanolin, Nicola Mattiuz, Elisa Battistuzzi, Marcello Beccari, Christian Geroin, Alessandro Picelli, Andreas Waldner, Nicola Smania
Frontiers in Neuroscience.2019;[Epub]     CrossRef
Low‐Frequency Brain Oscillations Track Motor Recovery in Human Stroke
Marlene Bönstrup, Lutz Krawinkel, Robert Schulz, Bastian Cheng, Jan Feldheim, Götz Thomalla, Leonardo G. Cohen, Christian Gerloff
Annals of Neurology.2019; 86(6): 853.     CrossRef
Phonomotor Versus Semantic Feature Analysis Treatment for Anomia in 58 Persons With Aphasia: A Randomized Controlled Trial
Diane L. Kendall, Megan Oelke Moldestad, Wesley Allen, Janaki Torrence, Stephen E. Nadeau
Journal of Speech, Language, and Hearing Research.2019; 62(12): 4464.     CrossRef
Sequential Transcriptome Changes in the Penumbra after Ischemic Stroke
In-Ae Choi, Ji Hee Yun, Ji-Hye Kim, Hahn Young Kim, Dong-Hee Choi, Jongmin Lee
International Journal of Molecular Sciences.2019; 20(24): 6349.     CrossRef
Triiodothyronine modulates neuronal plasticity mechanisms to enhance functional outcome after stroke
Daniela Talhada, Joana Feiteiro, Ana Raquel Costa, Tiago Talhada, Elisa Cairrão, Tadeusz Wieloch, Elisabet Englund, Cecília Reis Santos, Isabel Gonçalves, Karsten Ruscher
Acta Neuropathologica Communications.2019;[Epub]     CrossRef
Restorative Therapies after Stroke: Drugs, Devices, and Robotics
M. V. Padma Srivastava, Neha Kuthiala
Annals of the National Academy of Medical Sciences (India).2019; 55: 124.     CrossRef
Supporting recovery from brain injury
Simon Rumpel
Science.2018; 360(6384): 30.     CrossRef
Stimulating Dialogue Through Treatment of Poststroke Aphasia With Transcranial Direct Current Stimulation
Steven C. Cramer
JAMA Neurology.2018; 75(12): 1465.     CrossRef
Milestones in the history of thrombolytic therapy and limitations to use tPA
Yuko SUZUKI, Tetsumei URANO
Japanese Journal of Thrombosis and Hemostasis.2018; 29(5): 465.     CrossRef
Role of immune responses for extracellular matrix remodeling in the ischemic brain
Egor Dzyubenko, Daniel Manrique-Castano, Christoph Kleinschnitz, Andreas Faissner, Dirk M. Hermann
Therapeutic Advances in Neurological Disorders.2018; 11: 175628641881809.     CrossRef